منابع مشابه
Ulcerative Colitis and Immunoglobulin G4
BACKGROUND/AIMS Ulcerative colitis (UC) is sometimes associated with autoimmune pancreatitis (AIP). Infiltration of immunoglobulin G4 (IgG4)-positive plasma cells is sometimes detected in the colonic mucosa of AIP or UC patients. This study aimed to clarify the relation between UC and IgG4. METHODS Associations with UC were reviewed in 85 AIP patients. IgG4 immunostaining was performed on bio...
متن کاملElevated immunoglobulin G4 level is associated with reduced colectomy-free survival in patients with primary sclerosing cholangitis and ulcerative colitis.
BACKGROUND AND AIM Patients with primary sclerosing cholangitis (PSC) and elevated immunoglobulin (Ig) G4 have been shown to have more severe disease with a shorter time to orthotopic liver transplantation (OLT). The aim of the study was to investigate the clinical outcomes of PSC and UC in patients with elevated serum IgG4. METHODS We analyzed data from 50 patients with PSC and known serum l...
متن کاملImmunoglobulin G4 and related diseases.
i mmunoglobulins, produced by plasma cells, are the effector arm of the humoral immune system [1]. Each immunoglobulin consists of two identical heavy chains (α, β, γ, δ or ε – all encoded by chromosome 14) and two identical light chains (either κ or λ, encoded by chromosome 2 and 22, respectively) [2]. The immunoglobulins have constant (C) regions (similar within the same isotype) and variable...
متن کاملSerum Immunoglobulin G4 and Immunoglobulin G1 for Distinguishing Immunoglobulin G4-Associated Cholangitis From Primary Sclerosing Cholangitis
UNLABELLED The recent addition of immunoglobulin (Ig)G4-associated cholangitis (IAC), also called IgG4-related sclerosing cholangitis (IRSC), to the spectrum of chronic cholangiopathies has created the clinical need for reliable methods to discriminate between IAC and the more common cholestatic entities, primary (PSC) and secondary sclerosing cholangitis. The current American Association for t...
متن کاملPulmonary function in ulcerative colitis
Abstract Background: Pulmonary involvement in ulcerative colitis (UC) is thought to be rare. There is not a definite document about the question that "Is the lung a target organ in inflammatory bowel disease?" The aim of the present study is to compare lung function between cases with UC and healthy controls. This study will also be of interest about searching the outbreak of pulmonary functio...
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ژورنال
عنوان ژورنال: Gut and Liver
سال: 2014
ISSN: 1976-2283,2005-1212
DOI: 10.5009/gnl.2014.8.1.29